Padnarsertib (KPT 9274)
Product Specifications
CAS Number
1643913-93-2
Target
NAMPT
Applications
Metabolism
Smiles
C1CN (CCC1 (F) F) C (=O) C2=CC=C (C=C2) C3=CC (=C4C (=C3) C=C (O4) CNC (=O) C=CC5=CN=C (C=C5) N) C6=CC=C (C=C6) F
Molecular Formula
C35H29F3N4O3
Additionnal Information
Padnarsertib (KPT 9274) is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT. It shows an IC50 of ~120 nM for NAMPT in a cell-free enzymatic assay.
Storage Conditions
2 years -80 in solvent
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