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HPI-4 (Ciliobrevin A)

Product Specifications

CAS Number

302803-72-1

Synonyms

Hedgehog Pathway Inhibitor 4

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

C1=CC=C2C (=C1) C (=O) NC (=N2) C (=C (C3=C (C=C (C=C3) Cl) Cl) O) C#N

Molecular Formula

C17H9Cl2N3O2

Additionnal Information

HPI-4 (Ciliobrevin A, Hedgehog Pathway Inhibitor 4) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh) -induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.

Storage Conditions

2 years -80 in solvent

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