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Umbralisib (TGR-1202)

Product Specifications

CAS Number

1532533-67-7

Synonyms

Rp-5264

Target

PI3K

Applications

PI3K/Akt/mTOR

Smiles

CC (C) OC1=C (C=C (C=C1) C2=NN (C3=NC=NC (=C23) N) C (C) C4=C (C (=O) C5=C (O4) C=CC (=C5) F) C6=CC (=CC=C6) F) F

Molecular Formula

C31H24F3N5O3

Additionnal Information

Umbralisib (TGR-1202, Rp-5264), a novel, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 & 24.3 nM, respectively.

Storage Conditions

2 years -80 in solvent

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