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WAY-213613

WAY-213613 is a potent and selective inhibitor of the GLT-1/EAAT2 glutamate transporter (IC50 = 85 nM), exhibiting over 40-fold selectivity against EAAT1 and EAAT3 with no activity at glutamate receptors. This compound is a valuable pharmacological tool for in vitro and in vivo research into excitatory neurotransmission, astrocyte function, and conditions involving glutamate dysregulation.

Product Specifications

CAS Number

868359-05-1

Field of Research

Metabolism Research

Smiles

N[C@@H] (CC (=O) Nc1ccc (Oc2cc (F) c (F) cc2Br) cc1) C (O) =O

Molecular Formula

C16H13BrF2N2O4

Molecular Weight

415.19

Storage Conditions

-20°C

Notes

For research use only.

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