Poziotinib
Product Specifications
CAS Number
1092364-38-9
Synonyms
HM781-36B, NOV120101
Target
HER2
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=C2C (=C1) N=CN=C2NC3=C (C (=C (C=C3) Cl) Cl) F) OC4CCN (CC4) C (=O) C=C
Molecular Formula
C23H21Cl2FN4O3
Additionnal Information
Poziotinib is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Poziotinib also induces apoptosis and G1 cell cycle arrest. Phase 2.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7174620 Inquire
Rabbit anti-Escherichia coli O8 (strain IAI1) MLTC Polyclonal Antibody
Sign In for Pricing
View Details 
TL315388 1 Kit
PAP2D (PLPPR5) Human shRNA Plasmid Kit (Locus ID 163404)
Sign In for Pricing
View Details V2640-02X-FITC 100 µL
Von Hippel-Lindau Protein (vHL) (BSA & Azide Free) (FITC) discontinued
Sign In for Pricing
View Details