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Apabetalone (RVX-208)

Product Specifications

CAS Number

1044870-39-4

Synonyms

RVX-000222

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1=CC (=CC (=C1OCCO) C) C2=NC3=C (C (=CC (=C3) OC) OC) C (=O) N2

Molecular Formula

C20H22N2O5

Additionnal Information

Apabetalone (RVX-208, RVX-000222) is a potent BET bromodomain inhibitor with IC50 of 0.510 μM for BD2 in a cell-free assay, about 170-fold selectivity over BD1. Phase 2.

Storage Conditions

2 years -80 in solvent

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