JIB-04
Product Specifications
CAS Number
199596-05-9
Synonyms
NSC 693627
Target
Histone Demethylase
Applications
Epigenetics
Smiles
C1=CC=C (C=C1) C (=NNC2=NC=C (C=C2) Cl) C3=CC=CC=N3
Molecular Formula
C17H13ClN4
Additionnal Information
JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D in cell-free assays, respectively. JIB‐04 also induces cell apoptosis.
Storage Conditions
2 years -80 in solvent
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