SN-38
Product Specifications
CAS Number
86639-52-3
Synonyms
NK012
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
CCC1=C2CN3C (=CC4=C (C3=O) COC (=O) C4 (CC) O) C2=NC5=C1C=C (C=C5) O
Molecular Formula
C22H20N2O5
Additionnal Information
SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy.
Storage Conditions
2 years -80 in solvent
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