Sotrastaurin (AEB071)
Product Specifications
CAS Number
425637-18-9
Target
PKC
Applications
Cytoskeletal Signaling
Smiles
CN1CCN (CC1) C2=NC3=CC=CC=C3C (=N2) C4=C (C (=O) NC4=O) C5=CNC6=CC=CC=C65
Molecular Formula
C25H22N6O2
Additionnal Information
Sotrastaurin (AEB071) is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM in a cell-free assay; inactive to PKCζ. Phase 2.
Storage Conditions
2 years -80 in solvent
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