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GSK461364

Product Specifications

CAS Number

929095-18-1

Synonyms

GSK461364A

Target

PLK

Applications

Cell Cycle

Smiles

CC (C1=CC=CC=C1C (F) (F) F) OC2=C (SC (=C2) N3C=NC4=C3C=C (C=C4) CN5CCN (CC5) C) C (=O) N

Molecular Formula

C27H28F3N5O2S

Additionnal Information

GSK461364 (GSK461364A) inhibits purified Plk1 with Ki of 2.2 nM in a cell-free assay. It is more than 1000-fold selective against Plk2/3.

Storage Conditions

2 years -80 in solvent

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