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ENPP3 Inhibitor 1

ENPP3 Inhibitor 1 is a selective inhibitor of ENPP3, with IC50s of 0.15 µM (ENPP3) and 41.4 µM (ENPP1) respectively. ENPP3 Inhibitor 1 shows anti-tumor activities against breast cancer and cervical cancer[1].

Product Specifications

CAS Number

[2803505-90-8]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/enpp3-inhibitor-1.html

Concentration

10mM

Purity

99.43

Solubility

DMSO : ≥ 116.67 mg/mL

Smiles

O=C(C1=CC=CC=C1)NC2=CC=C(C=C2)OS(=O)(C3=CC=C(C=C3)OC(F)(F)F)=O

Molecular Formula

C20H14F3NO5S

Molecular Weight

437.39

References & Citations

[1]Ullah, et al. Synthesis and Biological Evaluation of Arylamide Sulphonate Derivatives as Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 and -3 Inhibitors. ACS Omega. 2022, 7 (30) :26905-26918.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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