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LCH-7749944

Product Specifications

CAS Number

796888-12-5

Synonyms

GNF-PF-2356

Target

PAK

Applications

Cytoskeletal Signaling

Smiles

COC1=CC=CC (=C1) NC2=NC3=CC=CC=C3C (=N2) NCC4CCCO4

Molecular Formula

C20H22N4O2

Additionnal Information

LCH-7749944 (GNF-PF-2356) is a novel and potent p21-activated kinase 4 (PAK4) inhibitor with an IC50 of 14.93 μM and has less potently inhibitory effect against PAK1, PAK5 and PAK6. LCH-7749944 causes successful inhibition of EGFR activity due to its inhibitory effect on PAK4.

Storage Conditions

3 years -20°C powder

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