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Selisistat (EX 527)

Product Specifications

CAS Number

49843-98-3

Synonyms

SEN0014196

Target

Sirtuin

Applications

DNA Damage/DNA Repair

Smiles

C1CC (C2=C (C1) C3=C (N2) C=CC (=C3) Cl) C (=O) N

Molecular Formula

C13H13ClN2O

Additionnal Information

Selisistat (EX 527, SEN0014196) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3. Phase 2.

Storage Conditions

2 years -80 in solvent

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