2,4,6-Trihydroxybenzaldehyde
Product Specifications
UNSPSC Description
2,4,6-Trihydroxybenzaldehyde is an orally active NF-?B inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity[1][2][3].
Target Antigen
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/2-4-6-trihydroxybenzaldehyde.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=CC1=C(O)C=C(O)C=C1O
Molecular Weight
154.121
References & Citations
[1]Kim KN, et al. 2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice. Environ Toxicol Pharmacol. 2015 Mar;39(2):962-8.|[2]Marton A, et al. Vanillin Analogues o-Vanillin and 2,4,6-Trihydroxybenzaldehyde Inhibit NFĸB Activation and Suppress Growth of A375 Human Melanoma. Anticancer Res. 2016 Nov;36(11):5743-5750.|[3]Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W005130/2-4-6-Trihydroxybenzaldehyde-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W005130/2-4-6-Trihydroxybenzaldehyde-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
487-70-7
Available Sizes
Curated Selection
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