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Pimasertib (AS-703026)

Product Specifications

CAS Number

1236699-92-5

Synonyms

MSC1936369B, SAR 245509

Target

MEK

Applications

Protein Tyrosine Kinase

Smiles

C1=CC (=C (C=C1I) F) NC2=C (C=CN=C2) C (=O) NCC (CO) O

Molecular Formula

C15H15FIN3O3

Additionnal Information

Pimasertib (AS-703026, MSC1936369B, SAR 245509) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 2.

Storage Conditions

2 years -80 in solvent

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