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DGCR14 Antibody

Product Specifications

Background

This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene (s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus.

NCBI Gene ID

8220

Swiss Prot

Q96DF8

Accession Number

Q96DF8

Host

Rabbit

Reactivity

Human

Immunogen

This DGCR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the Central region of human DGCR14.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DGCR14

NCBI Official Name

Protein DGCR14

NCBI Organism

Homo sapiens

Background Reference 01

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 02

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Wang, H., et al.Neural Transm 113 (10) :1551-1561 (2006)

Other Product Names

Protein DGCR14, DiGeorge syndrome critical region 13, DiGeorge syndrome critical region 14, DiGeorge syndrome protein H, DGS-H, Protein ES2, DGCR14, DGCR13, DGSH, DGSI, ES2

Tested Applications

WB

Protein ID

27805463

Physical Properties

Liquid

Frequently Asked Questions

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