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GSK467

Product Specifications

CAS Number

1628332-52-4

Target

Histone Demethylase

Applications

Epigenetics

Smiles

C1=CC=C (C=C1) CN2C=C (C=N2) OC3=NC4=C (C=CN=C4) C (=O) N3

Molecular Formula

C17H13N5O2

Additionnal Information

GSK467 is a cell penetrant and selective inhibitor of KDM5B (JARID1B/PLU1) with Ki of 10 nM. GSK467 shows apparent 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other JmJ family members.

Storage Conditions

3 years -20°C powder

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