J-113863
Product Specifications
CAS Number
353791-85-2
Additionnal Information
J-113863 is a potent and selective CCR1 antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM), but a weak antagonist of the mouse CCR3 (IC50 of 460 nM) . J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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