DGKα-IN-4
Product Specifications
CAS Number
2648723-43-5
Target
Others
Related Pathways
Others
Bioactivity
DGKα-IN-4 (example 432) is an inhibitor of DGKα with an IC50 value of 0.1 nM. This compound notably potentiates the anti-tumor efficacy of anti-PD-1 therapy by augmenting T cell proliferation and function and shows promise for research in cancer and immunology.
Smiles
C(#N)C1=C(C=2C(=CC(OC3CCOC3)=C(C#N)C2)N(C)C1=O)N4CCC(C)(CC4)C5=NC=6C(O5)=CC=C(C)C6
Molecular Formula
C30H29N5O4
Molecular Weight
523.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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