YB-3-17
Product Specifications
CAS Number
2940242-88-4
Target
MTOR
Applications
PI3K/Akt/mTOR
Molecular Formula
C38H39N11O6
Additionnal Information
YB-3−17 is a dual-target compound that effectively and selectively inhibits mTOR with an IC50 of 0.22 nM, while promoting GSPT1 degradation with an IC50 of 5 nM, leading to substantial tumor growth inhibition both in vitro and in vivo. It also exhibits significant antiproliferative activity in glioblastoma models.
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