MS41
Product Specifications
CAS Number
2768610-97-3
Target
Others
Applications
Others
Molecular Formula
C56H70N8O9S
Additionnal Information
MS41 is a highly potent and selective PROTAC degrader of eleven-nineteen leukemia (ENL) that recruits the von Hippel–Lindau (VHL) E3 ubiquitin ligase, with DC50 values of 3.50 nM (MV4;11), 2.84 nM (SEMK2), 3.03 nM (Jurkat), and 26.58 nM (KASUMI1) . It suppresses oncogenic gene expression, inhibits leukemia cell proliferation, and reduces MLL-r leukemia progression in a xenograft mouse model.
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15170175 1 Vial
Lentiviral mouse Kmt2e shRNA (UAS) - Lentiviral mouse Kmt2e shRNA (UAS, iRFP) (100)
Sign In for Pricing
View Details NBL1-17075 0.1 mg
TMEM38A Overexpression Lysate (Native) - (Dry Ice)
Sign In for Pricing
View Details