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FGFR3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Fibroblast growth factor receptor 3

Gene Aliases

ACH, CEK2, JTK4, CD333, HSFGFR3EX

Gene ID

2261

Swiss Prot

P22607

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human FGFR3, corresponding to a region within C-terminal amino acids

Target

FGFR3 a receptor tyrosine kinase of the highly-conserved FGFR family that binds fibroblast growth factor (FGF) . Mutations are associated with thanatophoric dysplasia (TD), craniosynostosis Adelaide type, many craniosynostotic syndromes and bone malformations. Three splice-variant isoforms have been described. Activating point mutations cause dwarfism, including achondroplasia, hypochrondroplasia and thanatophoric dysplasia, and facial and other morphogenetic disorders, including Crouzon syndrome, craniosynostosis Adelaide type, San Diego skeletal displasia and Muenke syndrome. Translocations t (4;14) involving the IgH region are common in multiple myeloma and frequently involve FGFR3.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC, ICF, IF

Purification

Purified by peptide affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid// PBS (pH 7.4) 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Reconstitution

Store at -20° C. Stable for 12 months from date of receipt.

Molecular Weight

95 kDa

Specificity

FGFR3 antibody detects endogenous levels of total FGFR3

NCBI Gene Symbol

FGFR3

Host or Source

Rabbit

Gene Name URL

FGFR3

Frequently Asked Questions

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