Nerve growth factor receptor (human) :Fc (human), (recombinant)
Product Specifications
Product Name Alternative
NGFR, TNFRSF 16, Low-affinity nerve growth factor receptor, p75NTR, p75 neurotrophin receptor, CD271
Certification
RUO
UniProt
P08138
Source
Produced in HEK 293 cells. The cysteine-rich domain of human NGFR (nerve growth factor receptor; p75 NTR) (aa 1-250) is fused to the Fc portion of human IgG1.
Stability
Stable for at least 6 months after receipt when stored at -20°C. After reconstitution, it is recommended to make appropriate aliquots and to store them at -20°C.
Concentration
1 mg/mL after reconstitution.
Endotoxin
<0.1EU/μg purified protein (LAL test; Bio Whittaker) .
Purity
≥90% (SDS-PAGE)
Reconstitution
Reconstitute in 50μl sterile water. Further dilutions can be made with medium containing 5% fetal calf serum.
Molecular Weight
~80kDa (under reducing conditions) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C
Notes
Historical data has shown that NGFR inhibits rat NGF-mediated activation of rat PC12 cells.
Specificity
Binds human, mouse and rat NGF (nerve growth factor) .
Formulation
Lyophilized. Contains PBS.
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