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CD134 (human) :Fc (human), (recombinant)

Product Specifications

Product Name Alternative

OX40, TNFRSF 4

Certification

RUO

UniProt

P43489

Source

Produced in HEK 293 cells. The cysteine-rich region of human CD134 (OX40) (aa 29-214) is fused to the Fc portion of human IgG1.

Stability

Stable for at least 6 months after receipt when stored at -20°C.

Concentration

1 mg/mL after reconstitution.

Endotoxin

<0.1EU/μg purified protein (LAL test; Bio Whittaker) .

Purity

≥95% (SDS-PAGE)

Reconstitution

Reconstitute with 50μl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.

Molecular Weight

~72kDa (SDS-PAGE) .

Shipping Conditions

Blue Ice

Storage Conditions

-20°C

Specificity

Binds human and mouse CD134L (OX40L) .

Formulation

Lyophilized. Contains PBS.

Applications Notes

ELISA: binds to CD134L) . Can be used together with anti-human IgG1 PAb to detect membrane-bound human CD134L. Has been used to ameliorate graft-versus-host disease, experimental allergic encephalomyelitis and inflammatory bowel disease.
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