What is the catalog number for LDN-193189?

The catalog number for LDN-193189 is C08723.

What sizes are available for LDN-193189?

LDN-193189 is available in the following size(s): 2 mg, 5 mg, 25 mg, 1 g.

How many pack sizes does LDN-193189 come in?

LDN-193189 is available in 4 different pack sizes.

Is LDN-193189 in stock?

LDN-193189 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for LDN-193189?

LDN-193189 is requires dry ice shipping.

LDN-193189

Product Specifications

CAS Number

1062368-24-4

Synonyms

DM3189

SKU

C08723-2mg

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

C1CN (CCN1) C2=CC=C (C=C2) C3=CN4C (=C (C=N4) C5=CC=NC6=CC=CC=C56) N=C3

Molecular Formula

C25H22N6

Additionnal Information

LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. For cell testing, the water-soluble S7507 LDN-193189 2HCl is recommended.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!