SGX-523

1022150-57-7

C07529-5mg

C-Met

Protein Tyrosine Kinase

CN1C=C (C=N1) C2=NN3C (=NN=C3SC4=CC5=C (C=C4) N=CC=C5) C=C2

C18H13N7S

SGX-523 is a selective Met (c-Met) inhibitor with IC50 of 4 nM, no activity to BRAFV599E, c-Raf, Abl and p38α. Phase 1.

2 years -80 in solvent

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