7β-Hydroxycholesterol
Product Specifications
CAS Number
566-27-8
SKU
C03951-5mg
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Additionnal Information
7β-Hydroxycholesterol is an oxysterol derived from the oxidation of cholesterol. It induces endothelial apoptosis, IL-1β secretion, and oxidative stress, leading to inflammation and organelle dysfunction. It also upregulates ICAM-1, VCAM-1, and E-selectin, thereby enhancing leukocyte adhesion in early atherosclerosis.
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