Afm24 (Anti-EGFR & Fc-gamma-RIIIA)
Selected Variant
C00912
Size: 1 mg
Product Specifications
Synonyms
Anti-EGFR/CD16A Bispecific Antibody AFM24
SKU
C00912-1mg
Target
EGFR
Applications
Protein Tyrosine Kinase
Additionnal Information
Afm24 is a human, tetravalent bispecific antibody targeting EGFR on tumor cells and the human low affinity IgG Fc region receptor IIIA (FCGR3A; CD16A) on innate immune cells. It enhances NK cell-mediated cytotoxicity and macrophage-driven phagocytosis, making it a promising immunotherapy with reduced EGFR-related toxicities for cancer treatment. M.W 196.34 kDa.
Storage Conditions
-80°C (avoid freeze-thaw cycles)
Price
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