Neurofilament Mouse mAb IHC Kit
Product Specifications
Background
Neurofilament (NF) is a neuron specific intermediate filament protein. It is a polymer composed of subunits of NF-H, NF-M and NF-L. It exists in neurons, neurites, peripheral nerve fibers, sympathetic ganglion cells and adrenal medulla. It is expressed in ganglioneuroma, paraganglioma, cerebellar or peripheral neuroblastoma, adrenal tumor or peripheral pheochromocytoma. It is helpful to the diagnosis and differential diagnosis of neuroblastoma and pheochromocytoma, and to identify the neurons of Hirschsprung's disease.
Synonyms
Neurofilament light polypeptide (NF-L, 68 kDa neurofilament protein, Neurofilament triplet L protein)
Gene Name
NEFL NF68 NFL
Gene ID
4747
Swiss Prot
P07196
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 543 of the human Neurofilament protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Neurofilament protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic
Protein Name
Neurofilament
Available Sizes
Frequently Asked Questions
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