TMP21 Recombinant Rabbit Monoclonal Antibody [PSH01-41]

Transmembrane emp24 domain-containing protein 10 is a protein that in humans is encoded by the TMED10 gene. This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

1110014C03Rik antibody 21 kDa transmembrane trafficking protein antibody 21 kDa transmembrane-trafficking protein antibody MGC102351 antibody p23 antibody p24 family protein delta 1 antibody p24 family protein delta-1 antibody p24 (DELTA) antibody p24delta antibody p24delta1 antibody S31I125 antibody S31III125 antibody TMED 10 antibody Tmed10 antibody TMEDA_HUMAN antibody Tmp 21 I antibody Tmp 21 antibody Tmp 21 I antibody Tmp-21-I antibody Transmembrane emp24 domain containing protein 10 antibody Transmembrane emp24 domain-containing protein 10 antibody Transmembrane emp24-like trafficking protein 10 (yeast) antibody Transmembrane protein Tmp21 antibody Transmembrane trafficking protein 21kD antibody

Abbreviation

TMED10, TMP21

Swiss Prot

P49755 Human, Q9D1D4 Mouse, Q63584 Rat

Cellular Locus

Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi apparatus membrane, Golgi apparatus, cis-Golgi network membrane, Golgi apparatus, trans-Golgi network membrane, Cytoplasmic vesicle, secretory vesicle membrane, Cell membrane, Melanosome.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human TMP21 aa 1-200 / 219.

Isotype

IgG

Clone

PSH01-41

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Tissue, IF-Cell, FC

Positive Control

HeLa cell lysate, 293T cell lysate, Raji cell lysate, Jurkat cell lysate, HepG2 cell lysate, U-87 MG cell lysate, PC-12 cell lysate, mouse pancreas tissue lysate, rat pancreas tissue lysate, rat liver tissue lysate, human breast tissue, human colon tissue, human liver tissue, mouse pancreas tissue, rat pancreas tissue, HeLa.