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PMEL/Melanoma gp100 (HMB45) Rabbit mAb IHC Kit

Product Specifications

Background

PMEL is a type I transmembrane glycoprotein which is specific in malanocyte. PMEL is abundantly expressed in melanosomes, and plays a central role in the biogenesis of melanosomes by involved in the maturation of melanosomes from stage I to II. It is highly expressed in all stages of melanoma progression, so the PMEL antibody can specifically labels melanoma cells.

Synonyms

95 kDa melanocyte specific secreted glycoprotein;95 kDa melanocyte-specific secreted glycoprotein; D12S53E; gp100; M-beta; ME20; ME20 M/ME20 S; ME20-M; ME20-S; ME20M; ME20M/ME20S; ME20S; Melanocyte lineage specific antigen GP100; Melanocyte protein mel 17; Melanocyte protein Pmel 17; Melanocyte protein Pmel 17 precursor; Melanocytes lineage-specific antigen GP100; Melanoma associated ME20 antigen; Melanoma gp100; Melanoma-associated ME20 antigen; Melanosomal matrix protein 17; Melanosomal matrix protein17; P1; p100; p26; PMEL 17; PMEL; PMEL_HUMAN; PMEL17; Premelanosome protein; Secreted melanoma-associated ME20 antigen; SI; SIL; SILV; Silver (Mouse homolog) like; Silver homolog; Silver locus protein homolog; Silver, Mouse, homolog of

Gene Name

PMEL

Gene ID

6490

Swiss Prot

P40967

Reactivity

Human; Mouse

Immunogen

A synthetic peptide corresponding to the amino acid region 400 - 500 of the human PMEL/Melanoma gp100 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human PMEL protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

Melanoma gp100

Available Sizes

Frequently Asked Questions

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