PMEL/Melanoma gp100 (HMB45) Rabbit mAb IHC Kit
Product Specifications
Background
PMEL is a type I transmembrane glycoprotein which is specific in malanocyte. PMEL is abundantly expressed in melanosomes, and plays a central role in the biogenesis of melanosomes by involved in the maturation of melanosomes from stage I to II. It is highly expressed in all stages of melanoma progression, so the PMEL antibody can specifically labels melanoma cells.
Synonyms
95 kDa melanocyte specific secreted glycoprotein;95 kDa melanocyte-specific secreted glycoprotein; D12S53E; gp100; M-beta; ME20; ME20 M/ME20 S; ME20-M; ME20-S; ME20M; ME20M/ME20S; ME20S; Melanocyte lineage specific antigen GP100; Melanocyte protein mel 17; Melanocyte protein Pmel 17; Melanocyte protein Pmel 17 precursor; Melanocytes lineage-specific antigen GP100; Melanoma associated ME20 antigen; Melanoma gp100; Melanoma-associated ME20 antigen; Melanosomal matrix protein 17; Melanosomal matrix protein17; P1; p100; p26; PMEL 17; PMEL; PMEL_HUMAN; PMEL17; Premelanosome protein; Secreted melanoma-associated ME20 antigen; SI; SIL; SILV; Silver (Mouse homolog) like; Silver homolog; Silver locus protein homolog; Silver, Mouse, homolog of
Gene Name
PMEL
Gene ID
6490
Swiss Prot
P40967
Reactivity
Human; Mouse
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 500 of the human PMEL/Melanoma gp100 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human PMEL protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic
Protein Name
Melanoma gp100
Available Sizes
Frequently Asked Questions
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