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IGF-2 Mouse mAb IHC Kit

Product Specifications

Background

Insulin-like growth factor II (IGF-2) is the protein hormones which belongs to the family of insulin-like growth factors that share structural similarity to insulin. It is secreted by the liver and circulates in the blood. In fetal, IGF-2 is a major growth factor that regulating fetoplacental development influenced by placental lactogen. It is also involed in tissue differentiation. In adults, IGF-2 is involved in glucose metabolism in liver, adipose tissue and skeletal muscle. It is an imprinted gene, expressed only from the paternal allele. Loss of imprinting is associated with Beckwith-Wiedemann syndrome.

Synonyms

C11orf43, IGF 2, IGF II, IGF-II, IGF2, IGF2_HUMAN, IGFII, INSIGF, insulin like growth factor 2 (somatomedin A), Insulin like Growth Factor 2, Insulin like growth factor II, Insulin like growth factor II precursor, Insulin like growth factor type 2, pp9974, Preptin, putative insulin like growth factor II associated protein, Somatomedin A, Somatomedin-A

Gene Name

IGF2

Gene ID

3481

Swiss Prot

P01344

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 1 - 100 of the human IGF - 2 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human IGF-2 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

IGF-2

Available Sizes

Curated Selection

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