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CGAS (AB2161) Rabbit mAb

Product Specifications

Background

Enables several functions, including 2', 3'-cyclic GMP-AMP synthase activity, molecular condensate scaffold activity, and phosphatidylinositol-4, 5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont, intracellular signal transduction, and regulation of defense response. Located in nuclear body, plasma membrane, and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Feb 2025]

Synonyms

Protein MB21D1 (Mab-21 domain-containing protein 1)

Gene Name

MB21D1 cGAS C6orf150

Gene ID

115004

Swiss Prot

Q8N884

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant protein (or fragment) . This information is considered to be commercially sensitive.

Clonality

Monoclonal

Source

Monoclonal, Rabbit, IgG

Applications

WB, IHC, IF, IP, ELISA

Purification

The antibody was purified by protein A affinity chromatography.

Dilution

WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Modification

Unmodified

Storage Conditions

Store at-20°C. Avoid freeze / thaw cycles.

Specificity

This antibody detects endogenous levels of cGAS protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Protein Name

CGAS

Available Sizes

Frequently Asked Questions

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