BA 1
BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1].
Product Specifications
CAS Number
183241-31-8
UNSPSC
12352209
Target
Bombesin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ba-1.html
Solubility
H2O
Smiles
O=C(CCNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](N)CC1=CC=C(O)C=C1)=O)CCC(N)=O)=O)CC2=CNC3=CC=CC=C23)=O)C)=O)C(C)C)=O)N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCC)=O)CC4=CC=CC=C4)=O)CC5=CNC=N5
Molecular Formula
C57H76N14O11
Molecular Weight
1133.30
References & Citations
[1]Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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