α‑Amylase-IN-1

α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC50 value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging DPPH free radicals. IC50 can be used in the study of diabetes and oxidative stress-related diseases.[1]

Product Specifications

CAS Number

[148404-10-8]

UNSPSC

12352005

Target

Amylases

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-amylase-in-1-1.html

Purity

98.33

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2=NN(C(C)=O)C(C3=CC=C(OC)C=C3)C2)C=C1

Molecular Formula

C18H18N2O3

Molecular Weight

310.35

References & Citations

[1]Ali A, et al. Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies. ACS Omega. 2023 Jun 2;8 (23) :20412-20422.