Box5 (TFA)
Product Specifications
UNSPSC Description
Box5 TFA is a potent Wnt5a antagonist. Box5 TFA inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca2+ release. Box5 TFA inhibits cell migration. Box5 TFA has the potential for the research of melanoma[1].
Target Antigen
Wnt
Type
Peptides
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/box5-tfa.html
Purity
94.71
Solubility
DMSO : 250 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CS)NC(CNC([C@H](CC(O)=O)NC([C@H](CCSC)NC(OC(C)(C)C)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Weight
880.90
References & Citations
[1]Jenei V, et al. A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19473-8.Oral Dis. 2024 May 8.|J Neuroinflammation. 2024 Mar 26;21(1):75.|Nano Today. 2024 Apr, 55, 102201.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123071A/Box5-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123071A/Box5-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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