2,5-Dihydroxyacetophenone
Product Specifications
UNSPSC Description
2,5-Dihydroxyacetophenone, isolated from Rehmannia glutinosa, inhibits the production of inflammatory mediators in activated macrophages by blocking the ERK1/2 and NF-κB signaling pathways[1].
Target Antigen
ERK; NF-κB
Type
Natural Products
Related Pathways
MAPK/ERK Pathway;NF-κB;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-5-dihydroxyacetophenone.html
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC(O)=CC=C1O)=O
Molecular Weight
152.149
References & Citations
[1]Han Y, et al. 2,5-dihydroxyacetophenone isolated from <i>Rehmanniae Radix</i> Preparata inhibits inflammatoryresponses in lipopolysaccharide-stimulated RAW264.7 macrophages. J Med Food. 2012 Jun;15(6):505-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W001174/2-5-Dihydroxyacetophenone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W001174/2-5-Dihydroxyacetophenone-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
490-78-8
Available Sizes
Curated Selection
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