What is the catalog number for Go 6983?

The catalog number for Go 6983 is HY-13689.

What sizes are available for Go 6983?

Go 6983 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 50 mg, 100 mg.

How many pack sizes does Go 6983 come in?

Go 6983 is available in 5 different pack sizes.

Go 6983 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Go 6983?

Go 6983 is manufactured by QuantiMol.

What is the estimated delivery time for Go 6983?

Estimated delivery time for Go 6983 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Go 6983?

The safety data sheet for Go 6983 is available here: http://file.medchemexpress.com/batch_PDF/HY-13689/Go-6983-SDS-MedChemExpress.pdf.

Go 6983

Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ, PKCδ and PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.

Product Specifications

CAS Number

133053-19-7

Product Name Alternative

Gö 6983; Goe 6983

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PKC

Type

Reference compound

Related Pathways

Epigenetics; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Go-6983.html

Concentration

10mM

Purity

99.23

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C(C1=CN(CCCN(C)C)C2=C1C=C(OC)C=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O

Molecular Formula

C26H26N4O3

Molecular Weight

442.51

Precautions

H302, H315, H319, H335

References & Citations

[1]Gschwendt M, et al. Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett, 1996, 392 (2), 77-80.|[2]Peterman EE, et al. G0 6983 exerts cardioprotective effects in myocardial ischemia/reperfusion. J Cardiovasc Pharmacol, 2004, 43 (5), 645-656.|[3]Young LH, et al. G0 6983: a fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury. Cardiovasc Drug Rev, 2005, 23 (3), 255-272.