Mouse GUCY2C Protein, His Tag

Description :Recombinant mouse GUCY2C protein with C-terminal6Ã-His tagBackground : Enables guanylate cyclase activity. Acts upstream of or within regulation of cell population proliferation and response to toxic substance. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in alimentary system and liver. Used to study abdominal obesity-metabolic syndrome and obesity. Human ortholog (s) of this gene implicated in congenital diarrhea 6. Orthologous to human GUCY2C (guanylate cyclase 2C) . Molecular Characterization: mass of 47.9 kDa after removal of the signal peptide. The apparent molecular mass of mGUCY2C-His is approximately 55-130 kDa due to glycosylation.Tag :C-6Ãƒâ€”His Tag

Product Specifications

Product Name Alternative

Gcc; GC-C

UniProt

Q3UWA6

Host

HEK293

Target Antigen

GUCY2C

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.