MR-2088
Product Specifications
UNSPSC Description
MR-2088 is a selective ULK1/ULK2 inhibitor with pEC50 values of 8.3 and 8.7, respectively. MR-2088 selectively inhibits autophagy through ULK1/2 mediated inhibition[1].
Target Antigen
Autophagy; ULK
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mr-2088.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC(F)(F)F)C1=CC(C2=CN=C3C(C=C(C4=CCCNC4)N3)=C2)=CS1
Molecular Weight
406.42
References & Citations
[1]Alisa Morozova, et al. Development of potent and selective ULK1/2 inhibitors based on 7-azaindole scaffold with favorable in vivo properties. European Journal of Medicinal Chemistry. 29 December 2023, 116101.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162100/MR-2088-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162100/
Clinical Information
No Development Reported
CAS Number
2922531-69-7
Curated Selection
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