Human EPHB3 Protein, His Tag

Description :Recombinant human EPHB3 Protein with C-terminal6Ã-His tagBackground : Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. Molecular Characterization: mass of 57.8 kDa after removal of the signal peptide. The apparent molecular mass of EPHB3-His is approximately 55-70 kDa due to glycosylation.Tag :C-6Ãƒâ€”His tag

Product Specifications

Product Name Alternative

EK2; ETK2; HEK2; TYRO6

UniProt

P54753

Host

HEK293

Target Antigen

EPHB3

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.