Human CD23 Protein, His Tag

The protein has a predicted molecular mass of 31.8 kDa after removal of the signal peptide. The apparent molecular mass of His-CD23 is approximately 35-55 kDa due to glycosylation. The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.