Polyclonal Antibody to Caveolin-2
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression.
Product Specifications
Product Name Alternative
CAV2
Gene Name
CAV2
Gene ID
858
UniProt
P51636
Host
Rabbit
Reactivity
Human
Immunogen
Target Antigen
Caveolin-2
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
1.0 mg/mL,100 μl
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 18 22kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
Frequently Asked Questions
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