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Polyclonal Antibody to Caspase 9

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Product Specifications

Product Name Alternative

ICE-like apoptotic protease 6

Gene Name

CASP9

Gene ID

842

UniProt

P55211

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around aa.301~305 (T-S-P-E-D) derived from Caspase 9

Target Antigen

Caspase 9

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 47 37 35kd, Western blotting: 1:1000

Isotype

Rabbit IgG

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