Anti-p63 Purified
The p53 family of proteins includes three members, p53, p63, and p73. The protein p63 is encoded by TP63 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp63) or absence (deltaNp63) of an N-terminal transactivation domain. Immunohistochemistry of p63 has a clinical relevance for certain tumor types, but investigations have been hampered by a lack of well characterized antibodies that are specific for p63 and do not cross-react with the related p53 and p73 proteins. Specificity :The mouse monoclonal antibody PANp63-6.1 recognizes both TAp63, and deltaNp63 form of p63. The target epitope PSHLIR is located within amino acids 261-266 of TAp63, and 167-172 of deltaNp63.
Product Specifications
Product Name Alternative
Tumor protein p63 TAp63 + deltaNp63, AIS, KET, LMS, NBP, RHS, EEC3, OFC8, SHFM4
Gene Name
TP63
Gene ID
8626
UniProt
Q9H3D4
Reactivity
Mouse
Immunogen
Recombinant full length human p63
Target Antigen
P63
Clonality
Monoclonal
Clone
PANp63-6.1
Applications
WB
Purification
Purified by protein-A affinity chromatography.
Format
Purified
Components
Concentration: 1 mg/mLStorage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Western blotting: Recommended dilution: 1 μg/mL
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