Anti-CD178 / Fas-L Monoclonal Antibody (Clone:NOK-1)
CD178 / Fas-L (Fas ligand, CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor CD95 / Fas. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE) . CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.
Product Specifications
Product Name Alternative
FASLG||APT1LG1||CD95L||FASL||TNFSF6
Gene Name
FASLG
Gene ID
356
UniProt
P48023
Host
Mouse
Reactivity
Human
Immunogen
L5178Y mouse T lymphoma cells expressing recombinant human CD178
Target Antigen
CD178 / Fas-L
Clonality
Monoclonal
Clone
NOK-1
Applications
FACS, IP, WB, ICC, Functional Assay
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Immunoprecipitation Western Blotting Immunocytochemistry Functional Application blocking
Isotype
Mouse IgG1
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