Human MBL2 Recombinant Rabbit Monoclonal Antibody [PSH04-86] - BSA and Azide free (Detector)
Mannose-binding lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity as an opsonin and via the lectin pathway. MBL belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL recognizes carbohydrate patterns found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding of MBL to a micro-organism results in activation of the lectin pathway of the complement system. Another important function of MBL is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.
Product Specifications
Product Name Alternative
Abbreviation
Mannose-binding protein C MBP-C Collectin-1 MBP1 Mannan-binding protein Mannose-binding lectin MBL2 COLEC1 MBL
Swiss Prot
P11226 Human
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human MBL2 aa 108-248 (P11226).
Isotype
IgG
Clone
PSH04-86
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Det)
Positive Control
Recombinant Human MBL2 protein (HA210628).
Concentration
1 mg/mL
Dilution
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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