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Monoclonal Antibody to Siglec-H (Clone: ABM2B55)

Siglec H (Sialic acid binding Ig-like lectin H) is cell surface protein of murine origin. Siglec H is mainly distributed in eosinophils and it binds to sialic acid. Siglec H lacks tyrosine based signaling motifs in its cytoplasmic tail, which gives it a special structural identity for binding sialic acid without binding with carbohydrates. Siglec H is specifically expressed in bone marrow, spleen, blood and lymph nodes.

Product Specifications

Product Name Alternative

Siglech||Siglec-H

Gene Name

Siglech

Gene ID

233274

UniProt

Q3Y597

Host

Rat

Reactivity

Mouse

Immunogen

A partial length recombinant mouse Siglec-H protein (amino acids 109-309) was used as the immunogen for this antibody.

Target Antigen

Siglec-H

Clonality

Monoclonal

Clone

ABM2B55

Applications

WB

Purification

Protein G Chromatography

Format

Purified

Components

25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blot analysis: 2-4 μg/mL

Isotype

Rat IgG2a Kappa

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