IL17RA Protein (C-human IgG1-Fc, Mouse)

Product Specifications

Abbreviation

IL17RA

Synonyms

Cdw217, Il17r, Il17ra, VDw217

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Measured by its binding ability in a functional ELISA. Immobilized mouse IL17A (Cat:51065-MNAE) at 10 μg/ml (100 μl/well) can bind mouse IL17RA-Fc (cat: 50328-M02H), The EC50 of mouse IL17RA-Fc (cat: 50328-M02H) is 0.28-0.64 μg/ml.

Function

Met1-Trp322

Molecular Weight

The recombinant mouse IL17RA/Fc is a disulfide-linked homodimer. The reduced monomer comprises 532 amino acids and has a predicted molecular mass of 60.3 kDa. The apparent molecular mass of the protein is approximately 67-77 and 118 kDa in SDS-PAGE under reducing conditions due to glycosylation.